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Regenerative Peripheral Nerve Interfaces for Improving Activities of Daily Living in People with Upper Limb Loss
Description: This project will obtain the regulatory approvals for a take-home clinical trial comparing surface EMG based myoelectric prosthetic control and intramuscular EMG with regenerative peripheral nerve interfaces (RPNIs).
Lab Contact: Bekah Perlin, M.S., bperlin@umich.edu
Collaborators: Cindy Chestek, Ph.D., Rachel Hooper, M.D., Theodore Kung, M.D., Paul Cederna, M.D.
Funding: NIH UG3NS131621-A1, Award Period: September 2025 - August 2027 (UH3 to follow)
A Unique Body-Powered Terminal Device with Enhanced Grasping Capabilities for Individuals with Upper Limb Loss
Description: This project will test a novel prosthetic end effector that enhances prosthetic grip force.
Lab Contact: Jessi Carlson, M.S., jessisc@umich.edu
PI: Harrison Bartlett, Ph.D., Little Room Technologies
Funding: 1R43HD115423-01A1 Award Period: September 2025 - February 2026
Regenerative Peripheral Nerve Interfaces for Restoring Individual Finger Movement in Transhumeral Amputees
Description: This project will determine the extent to which RPNIs enable generation of high-fidelity motor control signals for an advanced above-elbow prosthesis.
Lab Contact: Silke Kerstens, Ph.D., kerstens@umich.edu
Collaborators: Cindy Chestek, Ph.D., Rachel Hooper, M.D., Theodore Kung, M.D., Paul Cederna, M.D.
Funding: NIH 1R01HD116916-01, Award Period: Jan 2025 - December 2029
Improving hand kinematic predictions from implanted EMG in humans and monkeys
Description: This project will determine the extent to which RPNIs enable generation of high-fidelity motor control signals for an advanced above-elbow prosthesis.
Lab Contact: Mira Mutnick, M.S., mutnick@umiche.edu
PI: Cindy Chestek, Ph.D.
Collaborators: Rachel Hooper, M.D., Theodore Kung, M.D., Paul Cederna, M.D.
Funding: NIH 1R01NS134834-01A1, Award Period: July 2024 - June 2029
Regenerative Peripheral Nerve Interfaces (RPNIs) to Enhance Function and Sensation in People with Transfemoral Amputation
Description: This project will determine the extent to which RPNIs enable generation of high-fidelity motor control signals for an advanced above-knee prosthesis. We will also determine whether stimulation of RPNIs provides meaningful sensory feedback that can enhance stability. [Abstract]
Lab Contact: Jake Kanetis, M.S. jkanetis@umich.edu
Collaborators: Theodore Kung, M.D., Paul Cederna, M.D., Cindy Chestek, Ph.D., Elliott Rouse, Ph.D., Jeffrey Wensman, BSME, CPO
Funding: Department of Defense, Award Period: Sept 2023 – Aug 2027
Assessing the role of socket trim line on reactive balance in people with transfemoral amputation
Description: This study will determine if socket trim line affects the ability to utilize hip musculature and thus how people with transfemoral amputations respond to destabilizing forces. [Abstract]
Lab contact: Kristin Perrin, kperrin@umich.edu
Lab members: Kristin Perrin, Hiva Razavi
PI: Noah Rosenblatt, Ph.D.
Funding: Department of Defense, Award Period: Sept 2022 – Sept 2024
A holistic human-in-the-loop framework for optimizing a personalized prosthetic arm
Description: This project will develop a prosthesis emulator that moves the motor off board. This will enable us to optimize prosthetic function without the confounder of added weight. [project overview]
Lab Contact: CJ Nwokeabia. cnwoke@umich.edu
mPI: Jiyeon Kang, Ph.D.
Funding: National Science Foundation, Award Period: Sept 2022 – Sept 2025
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